Day 3 :
Keynote Forum
Miguel G Garber
Spanish Society of Regenerative Medicine and Cell Therapy, Spain
Keynote: The potential of regenerative medicine in heart and brain disease
Biography:
Miguel Garber has experience in Internal medicine and cardiology, with expertise in regenerative medicine, training and education, research, product development and senior management. He is currently working as Medical Director of Regeners Clinic (International Regenerative Medicine), ongoing of several investigative research involved Stem Cells application (ASC) and Drug stimulating stem cells (Aphanizomenón Flos Aquae), Professor and Clinical Director of the Master in Regenerative Medicine. He is also an Editorial Board Member.
Abstract:
Stroke and heart disease are leading causes of death. Both conditions share similar a number of risk factors, including smoking, high blood pressure, high cholesterol and diabetes. Chronic inflammation and changes in the blood vessels that bring blood to the brain and heart lead to a stroke or myocardial infraction. Imbalanced in neurotransmitters are responsible for responding to stress and affect heart and brain. Organ and tissue loss through disease and injury motivate the development of therapies that can regenerate tissues and decrease reliance on transplantations, applications of regenerative medicine technology, may offer novel therapies for patients with injuries, end-stage organ failure or other clinical problems. Since the underlying causes of heart attack and stroke are similar, therapies to treat stroke and heart attack are often similar, healthy lifestyle changes and nutritional supplements, hyperbaric oxygen, stem cell transplant, can dramatically reduce the risk of stroke and cardiac attack. The heart and brain maintain a continuous two-way dialogue each influencing the other’s functioning. The signals the heart sends to the brain can influence perception, emotional processing and higher cognitive functions. This system and circuitry is viewed by neuro-cardiology researchers as a heart brain communication. Actually we treat the cardiovascular heart failure and Alzheimer with good rate of recuperation with regenerative medicine life style changes, nutritional changes, nutritional supplements, hyperbaric oxygen, EECP (Increasing NO) and stem cell implants.
- Heart Disease & Brain Health | Neurocardiology | Spine surgery | Neurohormones | Pediatric Cardiology & Neurology
Location: Abu Dhabi
Session Introduction
Sabrina Zeghichi-Hamri
Bejaia University, Algeria
Title: Omega-3 fatty acids and malignant ventricular arrhythmias in patients with implantable cardioverter defibrillator
Biography:
Abstract:
Background: Studies that evaluated the effects of omega-3 polyunsaturated fatty acids (n-3) on cardiovascular diseases have yielded conflicting results. We aimed at examining the association between plant/marine n-3 and Malignant Ventricular Arrhythmias (MVA) among patients benefiting from the best preventive strategy including Implantable Cardioverter Defibrillator (ICD).
Method: Consecutive patients in whom an ICD was implanted for primary or secondary prevention of MVA were eligible. All patients had blood fatty acid analysis. The method of Kaplan-Meier was used to estimate the survival curves in each quartile of the main plant (ALA) and marine (EPA and DHA) n-3.
Results: Among the 238 enrolled patients, 100 had a relevant endpoint recorded by the ICD or died from a cardiac cause during a mean follow-up of 30±12 months. No significant difference in MVA was observed between quartiles of ALA (log-rank test p=0.88), EPA (log-rank test p=0.58) and DHA (log-rank test p=0.97). In a multivariate cox proportional hazard model including age, sex, ischemic heart disease, diabetes, smoking, hypertension and high cholesterol as covariates, we found no association between MVA and n-3: Hazard ratio was 1.12 (95% CI 0.62-2.02) for ALA and 1.44 (95% CI 0.81-2.58) for the sum of main marine n-3.
Conclusion: Plant and marine n-3 do not seem to either increase or decrease the risk of MVA in patients who are not n-3 deficient and benefit from the most effective preventive treatment. Further studies are required to test whether n-3 deficient patients would still benefit from n-3 supplements. Finally, these data raise major questions regarding interactions between dietary n-3 and certain medications.
- Workshop
Location: Abu Dhabi
Session Introduction
Anmar Homeida
Sudanese Medical Innovation Community, Sudan
Title: Supporting healthcare Startups: A new movement to accelerate cures in Sudan, the Middle East and Sub-Saharan Africa
Biography:
Anmar Homeida is the Founder and Team Leader, Executive Director of Sudanese Medical Innovation Community, Medical Education Development and Research Centre, Faculty of Medicine, University of Gezira. He is a Facilitator, Organizer and Founder of Startup Weekend Health, Wad Medani, Founder, Curator and Primary Organizer of TEDx, University of Gezira.
Abstract:
As one of the developing countries, Sudan has just emerged from a protracted period of conflicts that has brought disaster on its people, directly and indirectly. While some areas have witnessed war, others have suffered from the strain of hosting displaced populations. Others have been affected as a result of the diversion of resources meant for development. Startup Weekend Health-Wad Medani is a new movement to accelerate cure, change and empower the access to health for all. Our goal is to bring together the healthcare community, designers, IT professionals and entrepreneurs to facilitate the formation of new ideas. Startup Weekend Health-Wad Medani was held on the 4th-6th/August/2016 at the Cultural Palace Main Hall of Wad Medani and the buildings of Wad Medani College of Medical Science and Technology. There were more than 30 projects with wide, multi-disciplinary areas of experience; there were doctors, medical students, engineers, IT experts, etc. There were about 80 participants with different skill sets, including IT, finance, marketing, medicine and healthcare. By the end of the final pitches on the first day of the event, only 10 projects continued on to form teams. Examples of the winners who participated in the Startup Weekend event are Safer Life; a project aimed towards ending poor drug interactions by doing proper counseling for patients. SudaCare; a project oriented to support spreading medical knowledge for citizens. Now we have established the first office in the MEA region to support medical innovation among medical societies. We are here to fuel the spread of entrepreneurship in the healthcare and medicinal industry in Sudan, influencing the youth, doctors, professors and medical field students. We fully support the movement for better care, with cost effective practices that support our poor societies using inexpensive technology. Although we have taken a step in the right direction, we need the push to continue in innovation and entrepreneurship in these field-fueling more innovative projects that will accelerate cures for our society and the world.
Anmar Homeida
Sudanese Medical Innovation Community, Sudan
Title: Assessment of the prevalence of neurodevelopmental defects in patients with CHD patients in wad madani heart centre, July 2018
Biography:
Anmar Homeida is the Founder and Team Leader, Executive Director of Sudanese Medical Innovation Community, Medical Education Development and Research Centre, Faculty of Medicine, University of Gezira. He is a Facilitator, Organizer and Founder of Startup Weekend Health, Wad Medani, Founder, Curator and Primary Organizer of TEDx, University of Gezira.
Abstract:
Background: It is now well-appreciated that impaired fetal brain development and circulation, coexisting genetic syndromes, and pre-and postsurgical hemodynamic instability are equally important factors contributing to brain injury and neurodevelopmental outcome. Distinctive neurodevelopmental profiles in children with CHD are now recognized and include problems. With great advancements in the medical field and surgery, an impressive 90 percent of infants born with a congenital heart condition are able to survive until adulthood. The majority of these infants, however, often suffer from health problems including heart arrhythmia, neurodevelopmental deficiencies, autism and respiratory issues.
Method: We have started to work in Pediatric Cardiology clinic, checking the patients there, using cross-sectional study method after ethical approval from The Wad Madani heart center based on ethical committee of University of Gezira, Faculty of Medicine and Ministry of Health, which it may upgraded to large-scale longitudinal study and the measures will include behavioral data from 4-year-old neurodevelopmental evaluations and parent-report data from a later annual follow-up. We started to collect information from patients and co-patients after taking their permissions with a written consent.
Result: The results still under analysis and continuous collection of data.
Conclusion: With general positive results regarding the spreading of neurodevelopmental defects and Autism spectrum disorders which need focus from the medical teams throughout the world.